محققان جوانی که در مورد نوروفیبروماتوز کار می کنند و موفق به دریافت جایزه شده اند

دوستان عزیز:  انشالله به زودی برخی از این مطلب ترجمه خواهد شد. سایر محققان را در این سایت ملاحظه بفرمایید. انشالله کارهایشان به ثمر بنشیند http://www.ctf.org/item/2013-young-investigator-award-recipients-announced.html Shuning He, Harvard University, Dana-Farber Cancer Institute"In Vivo Analysis of the NF1 Tumor Suppressor in Neurofibromatosis"It is known that part of the NF1 protein down-regulates the function of another protein, called RAS, which can promote tumor formation when it is expressed at high levels. However, the functions of other regions of the NF1 protein have yet to be discovered. This project will study new functions of NF1 and how NF1 is involved in neurofibromatosis formation using a zebrafish model. When the functions of NF1 proteins are inhibited in zebrafish, they develop abnormally with defects that mirror the human disorder. The zebrafish model promises to be meaningful for the study of NF1 in humans and the development of improved therapies for patients with NF1.